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In addition the insulin target tissues, 264 transcriptome profiling and different studies have identified several -cell specific lncRNAs that contribute to obesity-mediated -cell dysfunction and apoptosis

One such form, ferroptosis, the so called death by iron, is induced by the ROS and intracellular lipid peroxidation that is catalyzed by iron

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Neuron 86 , 617631 (2015)

This dipeptide is then modified by an enzyme called glutathione synthetase, which adds glycine to form the tripeptide glutathione