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But I will say, JEEP, which I've done at least four orders with, has always been the smoothest
Semaglutide drives weight loss through appetite suppression and reduced caloric intake, not through enhanced fat oxidation
Trials still pending Two core obesity trials are still running: TRIUMPH-2 (obesity + type 2 diabetes) results expected later 2026 TRIUMPH-3 (obesity + established cardiovascular disease) results expected later 2026 A separate cardiovascular outcomes trial, TRIUMPH-Outcomes (~10,000 patients), is not required for the initial obesity NDA and wont report until 20282029
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Importantly, slow titration partially mitigates this
