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As Registered Dietitians, weve spent years helping clients understand why PCOS affects appetite, metabolism, and energy, and why the usual advice often falls flat
This is crucial for maintaining cellular integrity and function
As a result of that, initial recommendations focus on the use of metformin or a thiazolidinedione if metformin is contraindicated, followed by a GLP-1 agonist or a DPP-4 inhibitor
Scientific evidence says that 2 g or less L-carnitine per day is safe to take for those who want to lose weight
acetyl-LC) can promote characteristics of mitochondrial biogenesis, such as increased mitochondrial DNA and AMPK activity, and increased PGC1 , NRF-1 or mitochondrial transcription factor A protein levels, to counteract these mitochondrial dysfunctions (Reference Montesano, Senesi and Vacante72Reference Hota, Hota and Chaurasia77)
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