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Future studies using melatonin-competent mice, genetic validation of receptor independence, and time-of-day dosing paradigms will be critical to determine whether the melatoninglutathione axis can be exploited therapeutically to treat asthma

Sterile PBS: For in vitro cell culture applications (endothelial cell migration assays, fibroblast culture, etc.), prepare stock in sterile PBS and dilute into growth medium