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Palpitations / reflex tachycardia Fatigue Less Common Side Effects Nausea, abdominal pain Sleep disturbances Muscle cramps or joint pain Gingival hyperplasia (gum overgrowth, rare but possible with chronic use) Serious (but Rare) Side Effects Severe hypotension Arrhythmias (very rare) Allergic reactions (rash, itching, swelling) Liver dysfunction (rare, but check if jaundice or dark urine develops) Key Point for Patients Most frequent complaint = ankle edema

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most dramatic in 40+ users) Key requirement: Patience

Metformin (Oral Route)

Many insurance systems prioritise coverage for diseases such as diabetes, cardiovascular disease or hypertension