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The short half-life of native GLP-1, typically only 12 min due to rapid degradation, has facilitated the development of structurally modified GLP-1 analogs with longer half-lives, such as liraglutide, exendin-4, and dulaglutide, which exhibit 97%, 53%, and 90% sequence homology, respectively 12
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Published analyses of that trial and of SURMOUNT-1, a comparable trial of tirzepatide, have put lean tissue at roughly one quarter to 40 percent of total weight lost, depending on the trial and the method used
Apart from pain at the injection site, one of the risks of using lipotropic injections is that they may not work
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