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This pharmacokinetic profile provides a natural taper period, though patients should understand that appetite suppression and glycemic benefits will progressively decline during this window

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[15] [1] Nutritional adequacy : Reduced appetite and early satiety may lead to inadequate protein intake, vitamin deficiencies, or excessive muscle loss if not properly managed

We quickly recognized the need to risk-stratify patients undergoing endoscopy, Schulman, who co-chaired the panel, said