The G-site is more hydrophilic and exhibits a higher degree of sequence conservation within GST families than the H-site [42]
10.1007/s11307-018-1230-y Summary Keywords cancer, drug resistance, SSRI family, ABC transporters, ABCC1/MRP1, ABCC10/MRP7 Citation Bin Kanner Y, Teng Q-X, Ganoth A, Peer D, Wang J-Q, Chen Z-S and Tsfadia Y (2023) Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR
Glutathione is generally well-tolerated but can cause mild gastrointestinal side effects and, possibly, skin flushing
Advanced protocols under medical supervision may go up to 5 mg daily, though this is less common for skin applications
First, secondary death should occur in a spatially and temporally ordered manner that is consistent with directional spread rather than random coincidence