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Regular exercise supports nutrient exchange, joint lubrication, and the maintenance of cartilage and connective tissues, while adequate rest allows for repair, collagen formation, and long-term adaptation

(2016) 4:e00239

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These include orlistat (available on prescription or over the counter as Alli) and, more recently, semaglutide (Wegovy), which is recommended by NICE TA875 for use via NHS specialist weight management services in adults meeting defined BMI and comorbidity criteria

Some issues improve within weeks, while others require several months of structured rehabilitation