Mol Cell Endocrinol 306:4550
Alpha-lipoic acid, an antioxidant, has been shown to lessen the bad effects of fibrosis, a condition that can lead to cirrhosis and liver failure [58]
Carnitine (L-3hydroxy-4-trimethylaminobutyric acid), a water-soluble tetramine compound, is mainly distributed in tissues with high energy requirements, such as skeletal muscle and cardiac muscle
Agents such as quercetin, jujuboside A, cornuside, boeravinone C, cycloastragenol, and the JinChan YiShen TongLuo formula have been demonstrated to block TECs apoptosis through modulating mitochondrial function, ER stress, or key signaling pathways (117, 120, 128131), exhibiting promising translational potential
Rybelsus, the only oral GLP-1, is expected to be joined by Orforglipron by 2027-28