At this time, however, these conclusions are limited to speculation given the nature of a single case report
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For instance, exenatide, the first GLP-1-analogue developed, demonstrated to promote human monocyte differentiation into alternatively activated M2 macrophages, leading to an increase in anti-inflammatory cytokines such as IL-10 while significantly reducing pro-inflammatory cytokines, including IL-6, TNF- and IL-1 (43)