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In 2016, another balanced dual receptor agonist demonstrated pronounced effect on bodyweight and glucose control, together with reducing hepatic fat content in rodents and non-human primates (73)

The OCN dilution ratio used for immunofluorescence staining was 1:400 (abcam, USA)

Insulated travel cases with ice packs can maintain cold chain during flights or car trips lasting up to 24 hours

Repeated freezing and thawing 23 times (suggest frozen in liquid nitrogen, dissolved in 37 water bath)

For weight management, inadequate response (less than 5% weight loss after several months at maintenance dose) may warrant reassessment of the treatment approach