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Patients with diabetic retinopathy should be monitored closely, as rapid improvement in glycemic control has been associated with temporary worsening of diabetic retinopathy

The GCLC-KO mouse brain displays severe neuroinflammation at an early stage of brain atrophy Numerous studies have noted the importance of neuroinflammation in neurodegenerative processes 20

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In the study, a longer-acting version of the NK2R ligand was created by covalently attaching a 16-carbon fatty acid conjugate of -glutamic acid, which is the same moiety used in the GLP1RA liraglutide, to the Lys2 residue of native NKA