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Cells were incubated with QIs or parent compounds for 2.5 h, based on the time-dependency of QIs-induced loss of cell viability (Supplementary Figure S3)
Phase 3 results are expected throughout the remainder of the TRIUMPH program, with potential FDA approval estimated for 2027 at the earliest
Another clinical trial found that individuals who shifted their dinner to an earlier time and avoided late-night eating lost more weight and reported reduced cravings
However, these symptoms can also result from the caloric deficit associated with significant weight loss, adjustment to dietary changes, or pre-existing hormonal imbalances that become more apparent during metabolic transition
Most side effects are mild and manageable, especially when youre working with a provider who knows what to look for
