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Western blot analysis of thoracic aorta proteins showed that the classic aging markers P21 and P16 were significantly downregulated following FOXO4-DRI treatment, whereas the expression levels of the cell proliferation marker Ki-67 and Lamin B, a key protein involved in nuclear structural stability, were markedly upregulated (Figure 1A)

doi: 10.1002/mds.26563 183 WillkommenD.LucioM.MoritzF.ForcisiS.KanawatiB.SmirnovK

B12 deficiency can also cause water retention, constipation, muscle weakness, fatigue, and weight loss

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This bypasses the digestive system, ensuring maximum absorption and faster effects