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The ATTAIN-2 results reinforce the potential for orforglipron, as a once-daily oral, to deliver meaningful weight loss and A1C reduction, consistent with similar landmark trials for injectable GLP-1s, Custer added

The combination of sustained weight loss, improved metabolic markers, and enhanced quality of life makes GLP-1 injections a comprehensive solution rather than a temporary diet aid

Any substantial weight loss (on a GLP-1 or not) sheds some lean mass alongside fat

This strategy shows an early-adopter understanding of the evolving needs of health-focused consumers and the potential for growth within specialized nutrition markets

Nutrients 11, 214