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Astrocytes with low GSH may become less protective over time, releasing more inflammatory mediators and failing to supply an adequate amount of GSH and GSH precursors to neighboring neurons and microglia (Kwon et al., 2019
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Several biological processes rely on it to perform optimally, but levels diminish as we age, opening the door to premature cell death, aging, and age-associated diseases and conditions
19 has also reported dendrite disruption in hippocampal CA1 region and behavioral disorders in neuron-specific GCL knockdown mouse
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