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Despite their diverse pharmacological properties, these drugs converge on shared neurotoxic pathways, including oxidative stress, mitochondrial dysfunction, excitotoxicity, and neuroinflammation

Thanks, Len

They next established that mitochondrial Coenzyme Q counteracted ferroptosis triggered by pharmacological and genetic inhibition of GPX4, suggesting that mitochondrial lipid redox signaling regulates ferroptosis in AML cells

PMID 8492341

GS-conjugates are actively transported out of cells by efflux transporters including MRP1 and P-glycoprotein belonging to the superfamily of ATP-binding cassette transporters 70,71,72