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However, research protocols often compare systemic (subcutaneous) administration with localized administration to determine if one is more effective for a specific injury model.
During this period, brain growth is rapid, increasing the susceptibility to influences from the environment.27 This is also the period when most of the myelination of the brain occurs.9 In infants, moderate and severe vitamin B 12 deficiency has been associated with demyelination and brain atrophy.28 29 Little is known about the consequences of maternal vitamin B 12 deficiency for early brain myelination, neurodevelopment and cognitive function
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Additionally, radiation can disrupt skin microcirculation, leading to vascular permeability and vasoconstriction, resulting in skin tissue ischemia and hypoxia 19
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