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It is a serious, chronic, progressive disease tied to type 2 diabetes, cardiovascular disease, hypertension, stroke, fatty liver disease, sleep apnea, kidney disease, certain cancers, joint disease, depression, reduced mobility, and a lower quality of life
S.BouchezA.KrollA.FecklerA.et al (2021)
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A 2024 meta-analysis focusing on PCOS patients revealed that GLP-1 receptor agonists significantly lowered fasting insulin levels, improved results on the 2-hour postoral glucose tolerance test, and reduced HOMA-IR, a key marker of insulin resistance
The net effect is still overwhelmingly positive for most people, but it is worth being aware of
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