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Severe hypoglycemia caused 4 hospital-grade seizures or loss-of-consciousness events out of 71 patients in the Increlex program it is not a theoretical risk

Necrosis is promoted through cellular swelling (edema) and membrane depolarization due to calcium and water influx (97, 103, 106)

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doi: 10.1007/s12199-008-0073-6 158 TrullasRSkolnickP

Medication included