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Non-alcoholic steatohepatitis shows promise following survodutides 47% resolution rate in Phase 2, and chronic kidney disease is emerging as a major downstream indication based on FLOW outcomes

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Understanding an individual's genetic architecture in these pathways may support more informed medication selection and dose titration, though genetic predisposition does not determine exact treatment outcomes

We used incretin-responsive rat insulinoma-derived INS-1 832/3 beta cells to investigate differences between exendin-4 and lixisenatide in the native cellular context for GLP-1R

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