For patients with high triglycerides as a primary concern, this dual mechanism makes tirzepatide a particularly relevant option to discuss with a provider
4d), among which six ferroptosis-inhibiting genes (Slc7a11, Slc40a1, Gclm, Fth1, Gclc, and Gss) were upregulated, one ferroptosis-promoting gene (Slc39a14) was downregulated, and one ferroptosis-promoting gene (Hmox1) was upregulated
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Tirzepatide is a dual agonist that activates both GIP and GLP-1 receptors, which is thought to explain its larger average weight loss in clinical trials