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Hence, it is well protected from UV rays, pollution, and other environmental factors that may lead to lightening of the skin

Lexposition la pollution atmosphrique, aux rayons UV intenses et dautres facteurs environnementaux peut augmenter le stress oxydatif dans le corps

If you don't treat your B12 deficiency, it can lead to more severe neurological problems, including: Problems walking or speaking Vision loss Numbness or tingling Muscle weakness Difficulty remembering things Depression or mood swings Treating vitamin B12 deficiency Treatment depends on the reason for your low levels of B12

This occurs through several potential mechanisms: IGF-1 stimulates collagen synthesis and cartilage matrix expansion Growth signalling in synovial tissue may increase fluid production Systemic effects on sodium and water handling This side effect is typically mild and reversible

Ann Surg 1996, 223(4):420-427