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A 12-week multicenter randomized controlled trial provided strong evidence that for elderly people with sarcopenia or potential sarcopenia, the intervention of combined muscular-targeted oral nutritional supplements (rich in protein, HMB and vitamin D3) and structured exercise programs (including twin-weekly resistance training and interday chair exercises) compared with the control group It can more effectively improve the lean tissue of the limbs, skeletal muscle index, grip strength, walking speed, chair standing performance and quality of life [69]
Results vary by patient profile and dosage
The results showed a decrease in pro-inflammatory cytokines, specifically TNF, IL-1, and IL-6, along with reduced microglial activity in both spinal cord and brain tissues
Its also the name of the generic form of Victoza
The exercise group increased lean mass, and the combination group preserved lean mass despite significant fat loss
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