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Once in the central nervous system (CNS), the virus can either reside in a quiescent latent state in this tissue, or eventually actively lead to severe acute necrotizing encephalitis, which is characterized by exacerbated neuroinflammation and prolonged neuroimmune activation producing a life-threatening disease

Figure 1: Change in HbA1c at Week 24 and Change in HbA1c at Week 4, 8, 12, 16 and 20 Figure 2: Change from baseline FBG levels and PPBG levels Safety outcomes were comparable between the two groups, with adverse events reported in 56.7% of patients in both arms