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To test this hypothesis, German Holstein cows were assigned to a control group (CON, n = 26) and an L-carnitine supplemented group (CAR, n = 27, rumen-protected L-carnitine product: 125 g/cow/d, corresponded to total L-carnitine intake: 25 g/cow/d, supplied with concentrate) and received an intravenous bolus injection of lipopolysaccharides (LPS, 0.5 g/kg body weight, E
Some cases may require hospitalization for proper monitoring and treatment
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Outcome The outcome was incident cholangiocarcinoma, identified from the national cancer registers in each country (ICD 10 codes: C22.1, C23 and C24)