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Clinical evidence shows improvements in liver enzymes and reduction in hepatic steatosis, which is crucial for patients with metabolic syndrome or type 2 diabetes

For women using oral HRT, monitoring menopausal symptom control after initiating GLP-1/GIP therapy is advisable

However, intention-to-treat analysis showed no significant difference between the two groups, indicating the need for further large-scale randomized controlled trials to confirm these findings

In bone, exogenous and endogenous GIP is found to decrease bone resorption by reducing osteoclast activity and improving osteoblast survival (2527)

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