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## Availability Status: March 2026 - **FDA status:** Phase 3 clinical trials ongoing - **Expected approval timeline:** Potentially 2026-2027 - **Brand availability:** None yet - **Current access:** Compounding pharmacies (503A/503B) with valid prescription For a detailed breakdown of [retatrutide's FDA approval status and projected timeline](/guides/retatrutide-fda-approval-2026-timeline-status), see our dedicated tracker the date brand pricing becomes available depends directly on when retatrutide clears FDA review
doi: 10.1007/s10517-006-0365-z
The 2026 out-of-pocket cap is $2,100
GHK-Cu, short for glycyl-L-histidyl-L-lysine copper, is found naturally in human plasma, saliva, and urine, where it plays a critical role in tissue repair, skin renewal, and cellular regeneration
Weekly dosing is possible because the drugs are engineered with fatty acid chains that bind to albumin in the blood, extending their half-life
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