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Moreover, the first rate-limiting enzyme of the serine synthesis pathway, phosphoglycerate dehydrogenase (PHGDH), can couple with the RNA-binding protein poly (RC) binding protein 2 (PCBP2) and suppress its degradation, which plays a vital role in maintaining the stability of SLC7A11 mRNA and upregulates its expression, ultimately obstructing the development of ferroptosis [68]

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doi:10.1016/0014-5793(96)00631-X

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