[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment
Vitamin B 12 Vitamin B 12 , also known as cobalamin or extrinsic factor , is a water-soluble vitamin involved in metabolism
UK standard treatment regimens (per BNF and NHS guidance): Dietary deficiency (e.g., in vegans): oral cyanocobalamin 50150 micrograms daily between meals Pernicious anaemia or other absorption-related deficiency : intramuscular hydroxocobalamin 1 mg on alternate days for two weeks (loading), then 1 mg every two to three months as maintenance
However, if you experience any persistent or severe reactions, such as swelling, difficulty breathing, or other concerning symptoms, its important to contact your healthcare provider immediately
Trial durations were relatively short, typically 12 weeks maximum