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As a GLP-1 receptor agonist, semaglutide targets the appetite-regulating centers of the brain, reduces food cravings, and promotes feelings of fullness after smaller meals

Energy levels fluctuate during treatment, particularly during dose escalation

OCTN2 is a member of the SLC22 class of the solute carrier (SLC) transporter family that encompasses organic cation transporters (OCTs) and organic anion transporters (OATs)

Fair quality of methodology was considered in studies that enrolled only male subjects (population category) [14, 22, 25, 26, 28] or when blood sampling did not coincide with a steady state of an investigated drug [13,14,15,16,17, 19, 24]

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