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The panel agreed that initial treatment should be parenteral for severe cases, while high-dose oral B12 can be considered for maintenance
Oct 2022;46(10):1825-1832
Without adequate glutathione stores, Phase 1 toxic intermediates accumulate in the liver and bloodstream, causing severe systemic inflammation and triggering hypersensitivity reactions commonly seen in patients with complex chronic illnesses
These findings suggest that lung tumor cells have co-opted the system X c and EAAT3, a system typically associated with neurons, to facilitate GSH production
doi: 10.1074/jbc.M709040200 276 ThorleyA
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