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Cell Transplantation, 27 (9), 13131319
MC1R, melanogenesis and pigmentation MC1R is dominantly expressed in melanocytes in the skin, in hair follicles and in the iris of the eye
Specifically, the researchers suggested that the cleavage of caspase-3 and its substrate called Poly ADP-ribose polymerase (PARP) appeared markedly reduced, by ~43% and ~77% respectively, suggesting that the peptide complex may suppress this cascade of programmed cell death
PMID 16864745
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