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One 2017 study published in Scientific Reports showed that just 11 days of 5-Amino-1MQ led to measurable improvements in obesity-related biomarkers in mice fed a high-fat diet
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By selectively blocking NNMT, 5-Amino-1MQ is investigated for its ability to preserve cellular NAD+ pools, reduce methylation of nicotinamide to inactive 1-methylnicotinamide (1-MNA), and enhance sirtuin activity and energy metabolism
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