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GIP(1-30)NH 2 activates the GIP receptor with equivalent potency and efficacy as GIP(1-42) and elicits the same physiological effects on glucose- and bone metabolism in humans (13)
These metabolic effects of MT-II are mediated by binding to MC3R and MC4R, providing another intriguing use case for researchers interested in evaluating the MT-II peptide [24]
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However, twice-daily dosing doubles the number of times you need to perform the complete sublingual technique, which some people find inconvenient
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