This is highly speculative because: Oral bioavailability differs between species Route of administration affects systemic exposure Species differences in peptide metabolism and clearance are unknown Current Practice Patterns Current practice patterns from unregulated sources typically involve: Subcutaneous injection: 0.25-0.5 mg once or twice daily, administered near injection sites for localized effects or abdominally for systemic distribution
Injections are also advantageous for individuals who have undergone gastric surgery, as the procedure can: Decrease the number of cells needed to secrete stomach acid and intrinsic factor in the gastrointestinal tract Help bypass absorption challenges Provide adequate levels of the essential vitamin Immediate Increase in Blood Levels B12 injections can raise blood levels of the vitamin within 48 to 72 hours
But if your concerns are more systemic (e.g., eczema, chronic wounds), an injectable may be better indicated
[3] That framing is instructive: GHK-Cu may be most useful when tissue repair demand is high (post-surgery, injury, visible aging), which is also often the context in which sermorelin is prescribed for adults
20: Staresinic M, Japjec M, Vranes H, Prtoric A, Zizek H, Krezic I, Gojkovic S, Smoday IM, Oroz K, Staresinic E, Dretar V, Yago H, Milavic M, Sikiric S, Lovric E, Batelja Vuletic L, Simeon P, Dobric I, Strbe S, Kokot A, Vlainic J, Blagaic AB, Skrtic A, Seiwerth S, Sikiric P