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Each peptide has specific stability requirements, and combining them can cause aggregation, degradation, or altered pharmacokinetics

Nicotinamide N-Methyltransferase NNMT is a cytosolic methyltransferase that uses S-adenosyl-L-methionine to methylate nicotinamide

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2023 One caveat matters for anyone considering an oral form: in the same study, oral MOTS-c showed no significant benefit