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Magnesium deficiency may However, the research on magnesium supplements for muscle cramping is mixed

These include amino acids like cysteine (often supplemented as N-acetyl-cysteine, or NAC) and supporting minerals like selenium

Importantly, when polyphenols and topoisomerase II inhibitors were combined, it was possible to induce a synergistic decrease in cell proliferation (measured as ATP levels), cell-cycle arrest and induction of apoptosis in leukaemia cell lines

However, the available research suggests that results may be seen from doses as low as 5 mg per day (13)

It is most highly concentrated in the liver, where it is essential for both Phase I and Phase II detoxification pathways