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4) also caused inactivation of Akt-mTOR cascade in HUVECs, leading to decreased phosphorylation of Akt-S6K1 (Fig

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Novo Nordisk signs deal for monthly GLP-1 agonist Novo Nordisk is putting down up to US$362m to tap into Ascendis TransCon technology for treatments in metabolic and cardiovascular diseases

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If the proposed mechanism (gradual synaptic plasticity effects) is right, daily dosing might be needed for sustained effect