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This framework aligns with the multifactorial nature of neurodegeneration and ensures that interventions are matched not only to disease stage but also to individual patient biology and lifestyle

Oral B12 supplementation: High-dose oral cyanocobalamin (10002000 micrograms daily) represents an alternative for patients with dietary deficiency or those without severe deficiency or neurological symptoms, and for those unable or unwilling to receive injections

[PMID: 4913247] PubMed record related to this compound for laboratory literature review

Locato et al., 2017

Decreased antioxidant status in migraine patients with brain white matter hyperintensities