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271,272,273,274 Additionally, uric acid regulates MAPK through phosphatase activity that inhibits the MAPK pathway
Extensive efforts have been made in the past few years to improve therapeutic outcomes by depleting intracellular GSH
ERR and cardiac metabolism In a pressure-overload heart-failure mouse model, six weeks of SLU-PP-332 improved ejection fraction, reduced fibrosis, and increased survival
It has completed Phase 3 clinical trials (the REDEFINE program) with positive results, and Novo Nordisk is expected to seek FDA approval
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