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These improvements correlated with increased follicular copper levels and enhanced keratinocyte proliferation

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If given IV, it must be injected slowly (often over at least 5 minutes or diluted in a larger volume bag and infused)

Consistent with these findings, physiological measurements demonstrated that melatonin continued to improve airway function in the presence of Luzindole ( Figures 2O, P ), suggesting that receptor-independent mechanisms may contribute to melatonins protective effects in allergic airways disease

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