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The primary endpoint, change of weight loss over time, was analyzed by repeated-measures ANOVA comparing patients with GLP-1-RAs plus usual care weight management (GLP-1-RA group) to patients with usual care weight management only (UCWM)
This sets realistic timelines, helping reduce product abandonment, a common issue in which users stop too soon, missing out on benefits
Common reasons for stalled weight loss on semaglutide include liquid calories, mindless snacking despite reduced hunger, and insufficient protein intake that leads to muscle loss rather than fat loss
However, some insurance plans may cover semaglutide for weight loss
ImmunoTargets and Therapy, Volume 14, pp.359382
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