Although glucose causes a dose-dependent inhibition of pentose phosphate pathway activity in beta cells, the major pathway for NADPH production, the cytosolic ratio of NADPH/NADP + increases during glucose-stimulated insulin release
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Mikami, Y., Shibuya, N., Kimura, Y., Nagahara, N., Ogasawara, Y., and Kimura, H
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So, this action of the compound becomes essential for overall health