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Iron-chelating and ros-scavenging polymers with thioketal and thioether bonds delivering ferroptosis inhibitor lip-1 provide a triple therapeutic strategy for retina ganglion cells in acute glaucoma

Similar content being viewed by others Introduction Mitochondria are best studied for their ability to generate energy, but they are also essential for lipid homeostasis, ensuring proper Ca +2 storage inside the cells, and maintaining metabolomic balance 1,2,3,4,5

The primary outcome of the study was that the strain overproducing 6PGDH is the only one with an increased NADPH concentration, while no effect of the overproduction of G6PDH and TKL was observed