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Daily, the subjects were handled, weighed, and had their catheters flushed with a solution of cefazolin in heparinized saline
Injection site reactions (erythema, pruritus, swelling) occur in 1.4-2.4% of patients using subcutaneous formulations and are well-documented, localized effects
Bartels AL, Leenders KL
Its worth noting that in the context of drug delivery, the starting point for decay is when the max concentration of the drug from a single dose is reached
10.1371/journal.pone.0061965 59 SirohiS.SchurdakJ
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