The titration schedule plays a critical rolegradual dose escalation, as recommended in FDA labeling, allows for physiological adaptation and typically results in fewer and shorter-duration side effects compared to rapid dose increases
Seeing progress can be motivating
The body first empties ferritin, then, when no iron remains in reserve, hemoglobin production declines, red blood cells shrink, and oxygen delivery suffers
However, you SHOULD NOT take topiramate if you have kidney or liver disease, history of glaucoma, history of kidney stones, serious depression
GLP-1 receptor agonists, however, have a very similar composition to GLP1 but are designed to resist breakdown by DPP-4 (Figure 2)