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In Bca cells treated with brusatol, CHAC1 expression significantly rises, leading to GSH depletion, ROS buildup, and increased lipid peroxidation, which are key features of ferroptosis
Naunyn Schmiedebergs Arch Pharmacol 3:16 Nishida Y, Nawaz A, Kado T, Takikawa A, Igarashi Y, Onogi Y, Wada T, Sasaoka T, Yamamoto S, Sasahara M, Imura J (2020) Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway
S-Acetyl L Glutathione, which facilitates transport across cell membranes for efficient cellular uptake including the blood-brain barrier (Wu et al., 2004)
