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Through multifaceted mechanisms, miRNAs integrate oncogenic signaling with extrinsic stress responses, positioning them as key modulators of metabolic adaptation.miRNAs exert fine-tuned control over a wide array of metabolic pathways, including glycolysis, OXPHOS, fatty acid and amino acid metabolism, mitochondrial dynamics, and redox homeostasis [9]

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13 1 1057 8YW3 2024 Jul 17 Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide